The research team used mice that were manipulated genes controlling hunger. Enabling this gene right after weaning would prevent mice eating too much and become obese. Mice that maintaining a healthy weight by eating a healthy diet to maintain normal body weight without dieting after the gene is activated.But in overfed rats, weight who already ride can never go back to normal after the gene is activated. Though the mice had greatly reduced food intake and increased physical activity.
Therefore, the researchers then be doubts whether calorie restriction program and intensive exercise can help obese people lose weight for the long term in the future.If obesity is allowed to continue, will reprogram your body weight becomes heavier. Exact mechanism is still unknown and require much more research.
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